The Mutant Genes in the Early Onset Familial Alzheimer's – Part 1 - Alzheimer's 6

Previously, I posted about chromosomes related to the Alzheimer's disease and gene mutations as the genetic marker that believe to lead to this pathological disease.

Image 1- Simple talks of Alzheimer's patients

You may read previous postings (Part 1 and Part 2):

- In what chromosomes are the gene mutation related to Alzheimer's Disease? - Part 1 - Alzheimer's 5
- In what chromosomes are the gene mutation related to Alzheimer's Disease? - Part 2 - Alzheimer's 5

As we might know that the progressive declined in cognitive functions in Alzheimer's disease are associated with depositions of aggregated protein in form of extracellular plaques and neurofibrillary tangles in the brain.

Image 2- Plants, just for illustration

Image 3- Dialogs of normal and Alzheimer’s person.

Early-onset Alzheimer's disease appears about in the thirties and mid-sixties of the age which are characterized by the mutation of single gene in any chromosome in chromosome 1, chromosome 14 and chromosome 21.

Long investigations about the mutant gene that causes abundance of amyloid plaques were conducted.

Then the scientists found that this gene, the gene encoding amyloid precursor protein (APP), sits in chromosome 21.

It's an autosomal dominant.

# To be continued to Part 2

## Previous postings:

- Take Care of Winter Storm in Early 2022 – Part 2 – Nature 16
- The Early Person who Diagnosed with Alzheimer’s Diseases - Part 1 – Alzheimer's 2
- Sweet Chocolate Candies and a Yummy Book – Part 2 – Reading 8
- Reducing Number of Amazon River Pink Dolphin? - Part 1 – Nature 17