We might confuse with these two terms:
- Transgenic.
Transgenic is insertion of exogenous DNA into random non homologous site in the animal genome.
While Knockout is insertion of modified DNA at a specific homologous site in the animal genome.
It is interesting to discuss about knockout term furthermore in this posting.
In addition, knockout is the word commonly used to inactive an exist of specific gene in particular organism.
The way to knocked out is by replacing or disrupting the target gene with an artificial piece of DNA.
This is a genetic technique by using homologous recombination to change an endogenous gene.
Then, targeted gene could be permanent or conditional inactive or knockout.
Knockout could cause alter phenotype of organisms.
The changes might include behavior, appearance (observable physical) and biochemical characteristics of organisms.
Then, knockout organisms are used in learning about a gene that has been sequenced, which incompletely known function.
# To be continued to Part 2
# Previous postings:
- The Rainbow Before Evening : Russian Covid 19 Vaccine Advantages – Science 2
Animals always serve as guinea pigs for science we owe them a lot!
ReplyDeleteGood night wishes!
A hug, friend
Thanks-
DeleteWhat is Knockout Animals ? - Part 1- Science 8
-
Hi, dear, thanks for visiting, I'm here to pay you back, I'm in a hurry today, but I'll be back more often.
ReplyDeleteA hug and good night
Thanks-
DeleteWhat is Knockout Animals ? - Part 1- Science 8
-
Knockout mice, credit to National Human Genome Research Institute
We might confuse with these two terms:
- knockout
- Transgenic.
Transgenic is insertion of exogenous DNA into random non homologous site in the animal genome.
While Knockout is insertion of modified DNA at a specific homologous site in the animal genome.
It is interesting to discuss about knockout term furthermore in this posting.
In addition, knockout is the word commonly used to inactive an exist of specific gene in particular organism.
The way to knocked out is by replacing or disrupting the target gene with an artificial piece of DNA.
This is a genetic technique by using homologous recombination to change an endogenous gene.
Muy, muy, muy interesante.
ReplyDeleteThanks-
DeleteWhat is Knockout Animals ? - Part 1- Science 8
-
Garden corner, just illustration
Then, targeted gene could be permanent or conditional inactive or knockout.
Knockout could cause alter phenotype of organisms.
The changes might include behavior, appearance (observable physical) and biochemical characteristics of organisms.
Then, knockout organisms are used in learning about a gene that has been sequenced, which incompletely known function.
# To be continued to Part 2
# Previous postings:
- The Rainbow Before Evening : Making Perfume in the Organic Chemistry Laboratory - Science 1
- The Rainbow Before Evening : Russian Covid 19 Vaccine Advantages – Science 2
Very interesting
ReplyDeleteThanks-
DeleteWhat is Knockout Animals ? - Part 1- Science 8
Realmente muito interessante!
ReplyDeleteTe desejo um feliz fim de semana minha amiga!
Abraço
Thanks-
DeleteWhat is Knockout Animals ? - Part 1- Science 8
-
Knockout mice, credit to National Human Genome Research Institute
We might confuse with these two terms:
- knockout
- Transgenic.
Transgenic is insertion of exogenous DNA into random non homologous site in the animal genome.
While Knockout is insertion of modified DNA at a specific homologous site in the animal genome.
It is interesting to discuss about knockout term furthermore in this posting.
In addition, knockout is the word commonly used to inactive an exist of specific gene in particular organism.
The way to knocked out is by replacing or disrupting the target gene with an artificial piece of DNA.
This is a genetic technique by using homologous recombination to change an endogenous gene.
Olá, amiga!
ReplyDeleteInteressante e oportuna informação.
Votos de um excelente fim de semana!
Beijinhos!
Mário Margaride
http://poesiaaquiesta.blogspot.com
Thanks-
DeleteWhat is Knockout Animals ? - Part 1- Science 8
-
Garden corner, just illustration
Then, targeted gene could be permanent or conditional inactive or knockout.
Knockout could cause alter phenotype of organisms.
The changes might include behavior, appearance (observable physical) and biochemical characteristics of organisms.
Then, knockout organisms are used in learning about a gene that has been sequenced, which incompletely known function.
# To be continued to Part 2
# Previous postings:
- The Rainbow Before Evening : Making Perfume in the Organic Chemistry Laboratory - Science 1
- The Rainbow Before Evening : Russian Covid 19 Vaccine Advantages – Science 2
Grata pela interessante informação!
ReplyDeleteA ciência está sempre em constante evolução.
ReplyDeleteA temática é fascinante, mas é uma área acerca da qual tenho conhecimentos reduzidos.
Abraço amigo.
Juvenal Nunes
Thanks-
DeleteWhat is Knockout Animals ? - Part 1- Science 8
-
Garden corner, just illustration
Then, targeted gene could be permanent or conditional inactive or knockout.
Knockout could cause alter phenotype of organisms.
The changes might include behavior, appearance (observable physical) and biochemical characteristics of organisms.
Then, knockout organisms are used in learning about a gene that has been sequenced, which incompletely known function.
# To be continued to Part 2
# Previous postings:
- The Rainbow Before Evening : Making Perfume in the Organic Chemistry Laboratory - Science 1
- The Rainbow Before Evening : Russian Covid 19 Vaccine Advantages – Science 2
Muy interesante la información.
ReplyDeleteUn lindo fin de semana.
Abrazo
What is Knockout Animals ? - Part 1- Science 8
DeleteThanks-
ReplyDeleteWhat is Knockout Animals ? - Part 1- Science 8
-
Knockout mice, credit to National Human Genome Research Institute
We might confuse with these two terms:
- knockout
- Transgenic.
Transgenic is insertion of exogenous DNA into random non homologous site in the animal genome.
While Knockout is insertion of modified DNA at a specific homologous site in the animal genome.
It is interesting to discuss about knockout term furthermore in this posting.
In addition, knockout is the word commonly used to inactive an exist of specific gene in particular organism.
The way to knocked out is by replacing or disrupting the target gene with an artificial piece of DNA.
This is a genetic technique by using homologous recombination to change an endogenous gene.
Importante el tema de la ciencia. un abrazo
ReplyDeleteThanks-
DeleteWhat is Knockout Animals ? - Part 1- Science 8
-
Knockout mice, credit to National Human Genome Research Institute
We might confuse with these two terms:
- knockout
- Transgenic.
Transgenic is insertion of exogenous DNA into random non homologous site in the animal genome.
While Knockout is insertion of modified DNA at a specific homologous site in the animal genome.
It is interesting to discuss about knockout term furthermore in this posting.
In addition, knockout is the word commonly used to inactive an exist of specific gene in particular organism.
The way to knocked out is by replacing or disrupting the target gene with an artificial piece of DNA.
This is a genetic technique by using homologous recombination to change an endogenous gene.
new for me What is Knockout Animals ? - Part 1- Science 8
ReplyDelete